Avanti's Panama

Connecting Central and South America and the Atlantic to the Pacific, Panama is the crossroads of the Americas — and of cultures, landscapes, and traditions. From the misty cloud forests around Boquete, south to the bustling metropolis of Panama City, and out onto the islands of the Caribbean, Panama is a nation of startling variety, rich flora and fauna, and fascinating history.

Customized Vacations

Our Recommended Vacations are example itineraries crafted by our Product Managers to showcase how Avanti utilizes nearly 40 years of expertise to seamlessly connect the dots across Central & South America. They are completely customizable and can be tailored to meet the needs of your clients. Add a Folkloric Show in Panama City! Give your clients an extra night in Bocas del Toro so that they can explore all the bays, beaches, and islands in the area! Click the button to check out other Recommended Vacations for Central & South America.


Ultimate Panama:

Panama City, Boquete & Bocas del Toro

9 Days/8 Nights

More than its famous canal, Panama is a country of vibrant colors, rich traditions, and powder-soft beaches. Discover its wealth of culture and depth of flavor in this package that takes you from historic Panama City, to the bio-diverse Chiriqui Highlands for a awe-inspiring Skywalking Tour, before experiencing the sparkling archipelago of Bocas del Toro.


3 Nights Panama City | 2 Nights Boquete | 3 Nights Bocas del Toro


All Air & Ground Transfers | Culinary City Tour | Skywalk With Lunch | Bastimentos Marine National Park Tour with Lunch | Daily Breakfast


Panama Explorer:

Panama City, Valle de Anton, Playa Venao, Chitré & Boca Chica

10 days/9 nights

Discover Panama's wealth of culture and depth of flavor in this self-driving tour that takes you from historic Panama City to the seaside charms of Playa Venao, and the colonial flair of the Azuero Peninsula.


3 Nights Panama City | 1 Night Valle de Anton | 2 Nights Playa Venao | 1 Night Chitré | 2 Nights Boca Chica


Private Panama City & Canal Tour | Flight from David to Panama City | Private Airport Transfers | 6 Nights Automatic Car Rental | Daily Breakfast


Connecting Continents: Colombia & Panama

Bogotá, Cartagena, Portobelo & Panama City

13 Days/12 Nights

Bridging Central and South America, Colombia and Panama share a fascinating history replete with Conquistadores searching for gold and pirates assailing historic forts. They are also home to dynamic modern cities with delicious local specialties and lively markets. Learn about the storied past of these two countries while indulging in their contemporary delights and bio-diverse environments.


3 Nights Bogotá | 3 Nights Cartagena | 3 Nights Portobelo | 3 Nights Panama City


All Private Ground Transfers | Must Sees of Bogotá Tour | See and Taste Bogotá Tour | Sunday Usaquen Flea Market Bike Tour | Real Food, Real Places, Real People Tour | Getsemani Street Art Tour | Cartagena Colonial City Tour | Portobelo History, Custom House & Congos Tour with Lunch | Snorkeling at Drake Island with Lunch | Historic Portobelo & San Lorenzo Fort Tour with Lunch | Panama City Historic Tour | Camino de Cruces Trail Tour with Lunch | Daily Breakfast


Panama Handpicked Hotels

Recommended hotels, resorts, and more; personally inspected and selected by Avanti's travel professionals. Opt for over-the-water bungalows, or go for beach front eco-retreats. The choice is yours! Explore your Agent Portal for options.


Panama Tours and Experiences

Avanti strives to provide authentic and personalized experiences, including city tours, cooking classes, local family dinners, and more. From horseback riding to indigenous encounters, there's plenty of amazing offerings available. Check out your Agent Portal for options.



Here's some things to know before you go.


Panama Video

Learn about Panama from our exciting destination video!

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